An overview of various analytical approaches for the detection, identification, and control of critical impurities in phosphoramidites will be presented with a focus on UHPLC-MS methods capable of resolving isomeric and 2′-alkyl modified impurities.
Subject area:
Biologics
Objectives (If applicable):
NA
Target Audience (If applicable):
QA Manager
QA Staff
QC Chemist
QC Manager
R&D
Regulatory
Student